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    Journal of Dietitians Association of Nigeria (JDAN)Journal of Dietitians Association of Nigeria (JDAN)
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      Volume 10, 2019

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      • Volume 10, 2019
      • The Phytochemical Contents Of Telferia Occidentalis (Fluted Pumpkin) And The Effect Of Its Aqueous Extract On Blood Glucose And Enzymatic Antioxidant Of Stress Induced Rats

      The Phytochemical Contents Of Telferia Occidentalis (Fluted Pumpkin) And The Effect Of Its Aqueous Extract On Blood Glucose And Enzymatic Antioxidant Of Stress Induced Rats

      • Posted by Journal of Dietitians Association Nigeria
      • Categories Volume 10, 2019
      • Date December 16, 2019

      * 1Elejere Chidinma P, 1Okpara Chinedu E, 2Ukwujiagu Chiamaka U
      Dietetics Department, Alex Ekwuwme, Federal University Teaching Hospital Abakaliki
      Biochemistry Department, University of Nigeria Nsukka
      *Corresponding author: [email protected]
      ABSTRACT
      Background: Oxidative stress plays a major role in the development of chronic and degenerative diseases. The
      human body counteracts oxidative stress by producing antioxidants in situ or acquiring them through food.
      Objective: To determine the phytochemical content of T. occidentalis and the effects of its aqueous extract on
      some parameters in stress induced Wistar rats.
      Methods: The phytochemical content of the leaves was analysed using standard methods. Twenty adult male
      Wistar rats were divided into 4 groups of 5 rats each (3 test groups and 1 control group) and acclimatized for 3
      days. Persistent stress was induced using water immersion induced stress from the 4th to the 17th day. The stressed
      control group received animal feed and water only, while other stressed groups received animal feed, water and
      graded dosages of T.occidentalis for 14 days. Blood samples were collected before and after for biochemical
      parameters. The data obtained from the study were analysed using IBM SPSS Statistics version 21.0. Two way
      Analysis of Variance was performed and means were separated using Duncan’s new multiple range test.
      Significance level was set at p<0.05.
      Results: Flavonoid content of T.occidentalis was 32.60±0.20mg/100g, while alkaloids and carotenoids recorded
      496.49±1.37mg/100g and 28.79±0.38mg/100g, respectively. The group treated with T.occidentalis showed a
      significant (p<0.05) decrease in blood glucose when compared to the stress control. The group treated with the
      extract showed an increase (p<0.05) in catalase activity but a decrease (p<0.05) in malondialdehyde among the
      treatment groups of rats compared to the stress control group of rats after 14 day treatment period.
      Conclusion: This study has proven that Telferia occidentalis is safe for consumption and is an effective tool in
      stress management.
      Keywords: Telferia occidentalis, Phytochemicals, Blood glucose, Stress, Antioxidants

      Download Journal Here [614.69 KB]

      Tag:Antioxidants, blood glucose, phytochemicals, Stress, Telferia occidentalis

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      Journal of Dietitians Association Nigeria
      Journal of Dietitians Association Nigeria
      Dietitians Association of Nigeria (DAN) is an association of all dietitians in Nigeria. According to the International Confederation of Dietetic Association's (ICDA) definition, “a Dietitian is a person with a qualification in nutrition and dietetics recognized by national authority(s).

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